Pre-function area

Rialto Ballroom

    Chair: Hanna Wayment-Steele

• • Stephanie Wankowicz - Vanderbilt University, PI: Harnessing Conformational Ensembles and Entropy to Understand Evolutionary Determinants of Ligand Binding
  • Akashnathan Aranganathan - University of Maryland College Park, Graduate Student: Predicting Druggable Multi-Conformational Targets Using Boltzmann Ranking with AF2RAVE
  • Gina El Nesr - Stanford University, Graduate Student: Learning millisecond protein dynamics from what is missing in NMR spectra
  • Colin Smith - Wesleyan University, PI: Quantifying and correcting atomic resolution protein motion
  • Franke Noë - Microsoft Research AI for Science, PI: Discussant

Owens Ballroom

     Chair: Qian Cong

• Samantha Fischer - University of Illinois at Chicago, Graduate Student: Characterizing Mutually Exclusive Interactions with the hu.MAP3.0 Protein Complex Map
• Jing Zhang - University of Texas Southwestern Medical Center, Postdoc: Predicting the human interactome
• Guanhua He -  Stanford University, Postdoc: Novel macrocyclic peptide drug discovery platform using computational design and high-throughput screening

Pre-function area

Rialto Ballroom

     Session Chair: Terra Sztain

• • Alice Walker - Wayne State University, PI: Excited state simulations of fluorescent and photoactive proteins for rational design
  • Chris Jurich - UNC Chapel Hill, Graduate Student: Hybrid ML-physics methods to enanble virtual directed evolution
  • Catherine Kuhn - University of California, San Francisco, Graduate Student: Designing Metal Coordination driven Conformational Switches using Deep Learning

Owens Ballroom

     Session Chair: Jonathan Ash

• • Jonathan Ash - Rutgers University, Graduate Student: Prediction and Design of PDZ-PBM Interactions with Sequence and Structure-Based Deep Learning Methods
  • Harish Srinivasan - University of Texas Southwestern, Postbac Student: Designable Protein Sequence Generation with TriFlow
  • Matthew Hvasta - University of North Carolina, Chapel Hill, Graduate Student: Engineering a Complete Shell of Dengue Envelope Proteins Around a Self-Assembling Nanoparticle
  • Christian Schellhaas - École Polytechnique Fédérale de Lausanne, Graduate Student: Accurate Binder Design Using BindCraft

Rialto Ballroom

  What Does Quantum Chemistry Have to Say to Protein Design

   Session Chair: Matt O'Meara

Fairway Terrace (Tent)

Lunch Table: Docs & Tech support: Meet Hope Woods and Rachel Clune

Rialto Ballroom

     Session Chair: Cameron Glasscock

• • Hamish Blair - Stanford University, Graduate Student: Precise modelling of MaP-seq profiles
  • Andrew Favor / Andrew Kubaney - University of Washington, Graduate Students: De novo design of RNA and protein-nucleic complexes using multi-polymer diffusion
  • Renee Hastings - Stanford University, Graduate Student: Library-on-library measurements of in vitro protein–nucleic acid binding via a novel high-throughput microfluidic assay
  • Xiaonan Liu - Harvard University, Graduate Student: Interpret protein/genomic language models on protein coevolution

Owens Ballroom

     Session Chair: Chey Jones

• • Miles Woodcock-Girard - University of Illinois at Chicago, Graduate Student: A network of direct physical protein interactions derived from high throughput mass spectrometry experiments
  • Tanu Priya - Northwestern University, Graduate Student: Mapping Sequence–Function Relationships in a Model Enzyme Using High-Throughput Assays
  • Ramesh Jha - Los Alamos National Laboratory, PI: Thermophilic chassis-enabled high throughput screening for protein stability
  • Kosuke Seki - University of California, San Francisco, Postdoc: Traversing sequence-function landscapes in a tyrosine kinase with deep-learning guided design

• • Careers in Academia: Faculty Application Package - Miller - Hannah Wayment-Steele (UW-Madison), Terra Sztain (UMichigan), Stephanie Wankowicz (Vanderbilt)
  • Careers in Industry - Industry position Job Process - Owens - Chris Bahl (Chair), John Karanicolas (AbbVie), Jeff Ruffolo (Profluent), Jonathan Ziegler (Cradle), Deniz Kavi (Tamarind)
  • Science in the current environment - Rialto - Jeff Gray
  •  Inside the Journey: A Panel for Future Scientists - Craven - Alejandra Montaño Romero (JHU)
    • Trainee panel targeted for undergrads / beginning grads

Owens, until 4:35 PM

Roslyn Meadow

Rialto

Rialto Ballroom

     Computational design of conformation-biasing mutations to alter protein functions: application to a new proximity labeling enzyme, FlexID

   Session Chair: Kevin Drew

Rialto

Inside the Inn

Roslyn Meadow

• • Drinks and Snacks
  • With lawn games
  • Ends at 11:30